Tyrosinase Monoclonal Antibody (CAB21267)
- SKU:
- CAB21267
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
- IF
Frequently bought together:
Description
Product Name: | Tyrosinase Monoclonal Antibody |
SKU: | CAB21267 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Tyrosinase (NP_000363.1). |
Sequence: | FAHE APAF LPWH RLFL LRWE QEIQ KLTG DENF TIPY WDWR DAEK CDIC TDEY MGGQ HPTN PNLL SPAS FFSS WQIV CSRL EEYN SHQS LCNG TPEG PLRR N |
Tested Applications: | IHC-P IF/ICC ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3; Tyrosinase |
Conjugate: | Unconjugated |
Cellular Localization: | Melanosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 60kDa |
Observed MW: | Refer to figures |
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Purification Method: | Affinity purification |
Gene ID: | 7299 |
Clone Number: | ARC53166 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |