TYK2 Rabbit Polyclonal Antibody (CAB2128)
- SKU:
- CAB2128
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TYK2 Rabbit Polyclonal Antibody |
SKU: | CAB2128 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1102-1182 of human TYK2 (NP_003322.3). |
Sequence: | QSPP TKFL ELIG IAQG QMTV LRLT ELLE RGER LPRP DKCP CEVY HLMK NCWE TEAS FRPT FENL IPIL KTVH EKYQ GQAP S |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | JTK1; IMD35; TYK2 |
Positive Sample: | HeLa,Raji |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytoskeleton, cytosol, extracellular exosome, nucleus |
Calculated MW: | 134kDa |
Observed MW: | 134kDa |
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.
Purification Method: | Affinity purification |
Gene ID: | 7297 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |