TXNIP Polyclonal Antibody (CAB24289)
- SKU:
- CAB24289
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | TXNIP Polyclonal Antibody |
SKU: | CAB24289 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within human TXNIP. |
Sequence: | MVMF KKIK SFEV VFND PEKV YGSG EKVA GRVI VEVC EVTR VKAV RILA CGVA KVLW MQGS QQCK QTSE YLRY EDTL LLED QPTG ENEM VIMR PGNK YEYK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | THIF; VDUP1; ARRDC6; HHCPA78; EST01027; TXNIP |
Positive Sample: | Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 44kDa |
Observed MW: | 55kDa |
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10628 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |