The TXNIP Polyclonal Antibody is a powerful tool for researchers studying the TXNIP protein, which is involved in a variety of cellular processes including glucose metabolism, apoptosis, and oxidative stress. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.TXNIP, also known as thioredoxin-interacting protein, is a key regulator of redox balance in cells, playing a crucial role in mediating oxidative stress responses and controlling glucose uptake. Dysregulation of TXNIP has been implicated in various diseases, including diabetes, cardiovascular disorders, and cancer.
The ability to accurately detect and quantify TXNIP levels in different cell types makes this antibody an invaluable tool for researchers investigating the molecular mechanisms underlying these conditions.By using the TXNIP Polyclonal Antibody, researchers can gain important insights into the role of TXNIP in disease pathogenesis and potentially identify novel therapeutic targets for the treatment of TXNIP-related disorders. Its specificity and reliability make it a valuable asset for studies in the fields of cell biology, metabolism, and cancer research.
Product Name:
TXNIP Polyclonal Antibody
SKU:
CAB24289
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within human TXNIP.
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10628
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse thymus, using TXNIP Rabbit pAb (CAB24289) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
