UniProt Protein Function: | TXNDC8: May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm. Belongs to the thioredoxin family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 9q31.3Cellular Component: Golgi apparatus; cytoplasm; acrosomeMolecular Function: protein disulfide oxidoreductase activityBiological Process: acrosome formation; cell redox homeostasis; multicellular organismal development; spermatogenesis; glycerol ether metabolic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q6A555 |
NCBI GenInfo Identifier: | 51510891 |
NCBI Gene ID: | 255220 |
NCBI Accession: | NP_001003936.1 |
UniProt Secondary Accession: | Q6A555,Q5T934, A1L4I2, A6NDK7 |
UniProt Related Accession: | Q6A555 |
Molecular Weight: | 14,575 Da |
NCBI Full Name: | thioredoxin domain-containing protein 8 isoform a |
NCBI Synonym Full Names: | thioredoxin domain containing 8 (spermatozoa) |
NCBI Official Symbol: | TXNDC8Â Â |
NCBI Official Synonym Symbols: | TRX6; SPTRX-3; bA427L11.2Â Â |
NCBI Protein Information: | thioredoxin domain-containing protein 8; thioredoxin 6; sperm-specific thioredoxin 3; spermatid-specific thioredoxin-3; spermatocyte/spermatid-specific thioredoxin-3 |
UniProt Protein Name: | Thioredoxin domain-containing protein 8 |
UniProt Synonym Protein Names: | Spermatid-specific thioredoxin-3; Sptrx-3; Thioredoxin-6 |
Protein Family: | Thioredoxin domain-containing protein |
UniProt Gene Name: | TXNDC8Â Â |
UniProt Entry Name: | TXND8_HUMAN |