The TXNDC8 Polyclonal Antibody (PAC036390) is a valuable tool for research involving TXNDC8, a protein involved in redox regulation and cell signaling pathways. This antibody, raised in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the TXNDC8 protein, allowing for its detection and analysis in various cell types.TXNDC8, also known as thioredoxin domain-containing protein 8, plays a critical role in maintaining cellular redox balance and regulating diverse cellular processes. Its involvement in redox signaling pathways makes it a target of interest in studies related to oxidative stress, cancer, and neurodegenerative diseases.
Understanding the function of TXNDC8 is essential for unraveling its role in disease pathology and developing targeted therapies.Overall, the TXNDC8 Polyclonal Antibody is a valuable tool for researchers interested in studying TXNDC8 and its implications in various cellular processes and disease states. Its high reactivity and specificity make it ideal for use in immunology, cancer research, and other related fields.
Antibody Name:
TXNDC8 Antibody (PACO36390)
Antibody SKU:
PACO36390
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Thioredoxin domain-containing protein 8 protein (1-115AA)
Immunohistochemistry of paraffin-embedded human liver tissue using PACO36390 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human brain tissue using PACO36390 at dilution of 1:100.
Background:
May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.
TXNDC8: May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm. Belongs to the thioredoxin family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 9q31.3Cellular Component: Golgi apparatus; cytoplasm; acrosomeMolecular Function: protein disulfide oxidoreductase activityBiological Process: acrosome formation; cell redox homeostasis; multicellular organismal development; spermatogenesis; glycerol ether metabolic process
