TXNDC5 Rabbit Polyclonal Antibody (CAB14152)
- SKU:
- CAB14152
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TXNDC5 Rabbit Polyclonal Antibody |
SKU: | CAB14152 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-324 of human TXNDC5 (NP_001139021.1). |
Sequence: | MEDA KVYV AKVD CTAH SDVC SAQG VRGY PTLK LFKP GQEA VKYQ GPRD FQTL ENWM LQTL NEEP VTPE PEVE PPSA PELK QGLY ELSA SNFE LHVA QGDH FIKF FAPW CGHC KALA PTWE QLAL GLEH SETV KIGK VDCT QHYE LCSG NQVR GYPT LLWF RDGK KVDQ YKGK RDLE SLRE YVES QLQR TETG ATET VTPS EAPV LAAE PEAD KGTV LALT ENNF DDTI AEGI TFIK FYAP WCGH CKTL APTW EELS KKEF PGLA GVKI AEVD CTAE RNIC SKYS VRGY PTLL LFRG GKKV SEHS GGRD LDSL HRFV LSQA KDEL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:500 IF/ICC,1:50 - 1:100 |
Synonyms: | HCC2; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI; TXNDC5 |
Positive Sample: | HepG2,NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum lumen. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
Purification Method: | Affinity purification |
Gene ID: | 81567 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |