The TXNDC17 Polyclonal Antibody (PAC017347) is a valuable tool for researchers studying TXNDC17, a protein involved in redox regulation and oxidative stress response. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting TXNDC17 in human samples, making it suitable for Western blot applications. By binding to TXNDC17, this antibody enables the accurate assessment of TXNDC17 expression levels in various cell types, making it a valuable tool for investigations in the fields of oxidative stress, redox regulation, and cancer research.TXNDC17, also known as thioredoxin domain-containing protein 17, plays a crucial role in maintaining cellular redox balance and protecting cells from oxidative damage.
Dysregulation of TXNDC17 has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Understanding the functions of TXNDC17 is essential for developing targeted therapies aimed at restoring redox balance and combating oxidative stress-related pathologies.Overall, the TXNDC17 Polyclonal Antibody (PAC017347) offers researchers a reliable tool for studying the role of TXNDC17 in cellular redox homeostasis and its implications in disease pathogenesis. Its high specificity and sensitivity make it an ideal choice for researchers looking to advance their understanding of redox signaling pathways and develop novel therapeutic strategies.
Antibody Name:
TXNDC17 Antibody (PACO17347)
Antibody SKU:
PACO17347
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Full length fusion protein
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17347(TXNDC17 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-α signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
Synonyms:
thioredoxin domain containing 17
UniProt Protein Function:
Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.
