The TXNDC12 Polyclonal Antibody (CAB14403) is a valuable tool for researchers studying TXNDC12, a protein involved in redox regulation and protein folding in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TXNDC12 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and cell signaling pathways.
TXNDC12 plays a crucial role in maintaining cellular redox balance and promoting proper protein folding, making it a key player in cellular function and homeostasis. Its involvement in various biological processes makes it a potential target for research into diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases. Understanding the function of TXNDC12 is essential for developing targeted therapies that can modulate redox signaling and protein folding pathways in disease settings.
Product Name:
TXNDC12 Rabbit Polyclonal Antibody
SKU:
CAB14403
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 93-172 of human TXNDC12 (NP_056997.1).
This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
Purification Method:
Affinity purification
Gene ID:
51060
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TXNDC12 Rabbit pAb (CAB14403) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
