The TXN2 Polyclonal Antibody (CAB6782) is a crucial tool for research involving the thioredoxin protein TXN2, which plays a key role in regulating cellular redox balance and functions as a antioxidant enzyme. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TXN2 protein, this antibody enables precise detection and analysis in various cell types, making it an invaluable asset for studies in biochemistry and cancer research.Thioredoxin 2 (TXN2) is a critical player in maintaining cellular redox homeostasis and protecting cells from oxidative stress-induced damage.
Dysregulation of TXN2 has been implicated in a variety of diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. By studying the function and expression of TXN2 using this antibody, researchers can gain insight into the role of this protein in disease pathogenesis and identify potential therapeutic targets for intervention. Understanding the mechanisms by which TXN2 influences cellular function is essential for developing effective treatments that target oxidative stress-related diseases.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human Thioredoxin 2 (Trx2/Thioredoxin 2 (Trx2/TXN2)) (NP_036605.2).
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
Purification Method:
Affinity purification
Gene ID:
25828
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Thioredoxin 2 (Trx2/Thioredoxin 2 (Trx2/TXN2)) antibody (CAB6782) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
