The TXN2 Polyclonal Antibody (CAB12591) is a powerful research tool specifically designed for studying Thioredoxin 2 (TXN2), a key mitochondrial protein involved in redox regulation and cell signaling. This high-quality antibody, produced in rabbits, has been extensively validated for use in various applications, including Western blot and immunohistochemistry.Thioredoxin 2 is a crucial player in maintaining cellular redox balance and protecting cells from oxidative stress. Dysregulation of TXN2 has been linked to various diseases, such as cancer, neurodegenerative disorders, and cardiovascular diseases.
By using the TXN2 Polyclonal Antibody, researchers can accurately detect and analyze TXN2 levels in different cell types and tissues, allowing for a deeper understanding of its role in disease development and progression.The TXN2 Polyclonal Antibody is a valuable asset for scientists and researchers interested in exploring the functions and mechanisms of Thioredoxin 2 in health and disease. With its high specificity and sensitivity, this antibody is an essential tool for advancing research in the fields of molecular biology, biochemistry, and biomedical sciences.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human Thioredoxin 2 (Trx2/Thioredoxin 2 (Trx2/TXN2)) (NP_036605.2).
Raji,293T,SW620,Mouse liver,Mouse brain,Mouse bone marrow
Conjugate:
Unconjugated
Cellular Localization:
Mitochondrion.
Calculated MW:
18kDa
Observed MW:
13kDa
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.
Purification Method:
Affinity purification
Gene ID:
25828
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Thioredoxin 2 (Trx2/Thioredoxin 2 (Trx2/TXN2)) antibody (CAB12591) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
