The TXNDC5 Polyclonal Antibody (CAB15865) is a valuable tool for researchers studying the TXNDC5 protein, an important player in redox homeostasis and cellular responses to oxidative stress. This antibody, derived from rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TXNDC5 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for studies in cell biology and oxidative stress research.
TXNDC5, also known as thioredoxin domain-containing protein 5, plays a crucial role in maintaining cellular redox balance and protecting cells from oxidative damage. Its involvement in redox signaling pathways makes it a key target for research on aging, neurodegenerative diseases, and cancer, where oxidative stress is a contributing factor. Understanding the function of TXNDC5 is essential for developing strategies to mitigate oxidative damage and improve cellular health in various disease states.
Product Name:
TXLNG Rabbit Polyclonal Antibody
SKU:
CAB15865
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TXLNG (NP_060830.2).
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55787
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TXLNG Rabbit pAb (CAB15865) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 150s.
