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TWF2 Polyclonal Antibody (CAB21353)

SKU:
CAB21353
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
IP
$155 - $431
Frequently bought together:

Description

TWF2 Polyclonal Antibody (CAB21353)

The TWF2 Polyclonal Antibody (CAB21353) is a valuable tool for researchers studying the TWF2 protein, which plays a key role in cell motility and cytoskeletal organization. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the TWF2 protein, this antibody enables the detection and analysis of TWF2 in various cell types, making it ideal for investigations in cell biology, cancer research, and other fields.

TWF2, also known as Twinfilin-2, is involved in the regulation of actin dynamics and cellular processes such as cell migration, adhesion, and morphogenesis. Its functions make it a promising target for research into diseases characterized by abnormal cell motility, such as metastatic cancer. By studying the role of TWF2, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.

Product Name:TWF2 Polyclonal Antibody
Product Code:CAB21353
Reactivity:Human
Applications:Immunoprecipitation
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:IP, ELISA
Key Applications:Immunoprecipitation
Recommended Dilution:IP 50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location:Cell projection, Cytoplasm, cytoskeleton, perinuclear region, stereocilium

The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human TWF2 (NP_009215.1).
Sequence:MAHQT GIHAT EELKE FFAKA RAGSV RLIKV VIEDE QLVLG ASQEP VGRWD QDYDR AVLPL LDAQQ PCYLL YRLDS QNAQG FEWLF LAWSP DNSPV RLKML YAATR ATVKK EFGGG HIKDE LFGTV KDDLS FAGYQ KHLSS CAAPA PLTSA ERELQ QIRIN EVKTE ISVES KHQTL QGLAF PLQPE AQRAL QQLKQ KMVNY IQMKL DLERE TIELV HTEPT DVAQL PSRVP RDAAR YHFFL YKHTH EGDPL ESVVF IYSMP GYKCS IKERM LYSSC KSRLL DSVEQ DFHLE IAKKI EIGDG AELTA EFLYD EVHPK QHAFK QAFAK PKGPG GKRGH KRLIR GPGEN GDDS
Synonyms:A6r, A6RP, PTK9L, MSTP011
Calculated MW:40kDa
Observed MW:Refer to figures

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