The TWF1 Polyclonal Antibody (CAB15307) is a valuable tool for researchers studying TWF1, a protein involved in cell migration and cytoskeletal dynamics. Raised in rabbits, this antibody is highly specific for human samples and is validated for use in Western blotting applications. By binding to the TWF1 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for research in cell biology, cancer metastasis, and drug development.TWF1, also known as twinfilin-1, plays a crucial role in regulating actin dynamics and cell movement, making it a key protein in processes such as cell migration and invasion.
Its involvement in cytoskeletal rearrangements underscores its importance in cancer progression and metastasis, making it a promising target for novel therapeutics and diagnostic tools. By understanding the function of TWF1, researchers can uncover new insights into cancer biology and potentially develop targeted therapies to impede tumor spread.
Product Name:
TWF1 Rabbit Polyclonal Antibody
SKU:
CAB15307
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 101-350 of human TWF1 (NP_002813.3).
This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.
Purification Method:
Affinity purification
Gene ID:
5756
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TWF1 Rabbit pAb (CAB15307) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
