The TUSC5 Polyclonal Antibody (PAC020794) is a key tool for researchers studying the TUSC5 protein, which is known to play a critical role in glucose and lipid metabolism. This antibody, produced in rabbits, has been shown to have high specificity and sensitivity for detecting TUSC5 in human samples, making it a valuable tool for a variety of research applications including Western blot analysis.TUSC5, also referred to as tumor suppressor candidate 5, is involved in regulating glucose uptake and metabolism in cells, making it an important target for research in metabolic disorders and cancer. By detecting and analyzing TUSC5 expression levels in different cell types, this antibody can provide valuable insights into the molecular mechanisms underlying metabolic dysfunction and potential therapeutic strategies for related diseases.
With its ability to specifically target TUSC5, the PAC020794 antibody is a reliable tool for researchers looking to further investigate the role of TUSC5 in metabolic regulation and its implications for human health. Its versatility and compatibility with various research techniques make it a valuable asset for studies in the fields of metabolism, diabetes, and cancer research.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20794(TUSC5 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 12%SDS-PAGE,Lysate: 40 µg,Lane 1-2: Lovo cells, 231 cells,Primary antibody: PACO20794(TUSC5 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20794(TUSC5 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
TUSC5 (tumor suppressor candidate 5), also known as protein located at seventeen-p-thirteen point three 1, LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3), is a 177 amino acid, multi-pass membrane protein that belongs to the CD225 family. Thought to play a role in fat metabolism, TUSC5 is highly expressed in mammary gland, heart, smooth muscle, skeletal muscle and stomach, with lower levels found in lung and brain.
Synonyms:
tumor suppressor candidate 5
UniProt Protein Function:
TUSC5: May be involved in fat metabolism. Belongs to the CD225/Dispanin family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17p13.3
Dispanin subfamily B member 1; DSPB1; Interferon-induced transmembrane domain-containing protein D3; Protein located at seventeen-p-thirteen point three 1
