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Anti-TUSC2 Antibody (CAB7075)

SKU:
CAB7075
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle
  • Cell Cycle Antibodies 2 Anti-TUSC2 Antibody CAB7075
  • Cell Cycle Antibodies 2 Anti-TUSC2 Antibody CAB7075
  • Cell Cycle Antibodies 2 Anti-TUSC2 Antibody CAB7075
  • Cell Cycle Antibodies 2 Anti-TUSC2 Antibody CAB7075
€139 - €419
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Description

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Antibody Name:Anti-TUSC2 Antibody
Antibody SKU:CAB7075
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TUSC2 (NP_009206.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human TUSC2 (NP_009206.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGAS GSKA RGLW PFAS AAGG GGSE AAGA EQAL VRPR GRAV PPFV FTRR GSMF YDED GDLA HEFY EETI VTKN GQKR AKLR RVHK NLIP QGIV KLDH PRIH VDFP VILY EV
Gene ID:11334
Uniprot:O75896
Cellular Location:
Calculated MW:12kDa
Observed MW:Refer to Figures
Synonyms:TUSC2, C3orf11, FUS1, PAP, PDAP2
Background:This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available.
UniProt Protein Function:TUSC2: May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. Belongs to the TUSC2 family.
UniProt Protein Details:

Protein type:Tumor suppressor

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion

Biological Process: interleukin-15 production; cell proliferation; negative regulation of interleukin-17 production; regulation of mitochondrial membrane potential; cell-cell signaling; natural killer cell differentiation; response to defense-related host reactive oxygen species production; cell maturation; cell cycle; inflammatory response; positive regulation of interleukin-10 production; phagocytosis

NCBI Summary:This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008]
UniProt Code:O75896
NCBI GenInfo Identifier:7531123
NCBI Gene ID:11334
NCBI Accession:O75896.3
UniProt Secondary Accession:O75896,B2R4Y9,
UniProt Related Accession:O75896
Molecular Weight:110
NCBI Full Name:Tumor suppressor candidate 2
NCBI Synonym Full Names:tumor suppressor candidate 2
NCBI Official Symbol:TUSC2  
NCBI Official Synonym Symbols:PAP; FUS1; PDAP2; C3orf11  
NCBI Protein Information:tumor suppressor candidate 2; fus-1 protein; fusion 1 protein; PDGFA associated protein 2; PDGFA-associated protein 2
UniProt Protein Name:Tumor suppressor candidate 2
UniProt Synonym Protein Names:Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2
Protein Family:Tumor suppressor candidate
UniProt Gene Name:TUSC2  
UniProt Entry Name:TUSC2_HUMAN
Anti-TUSC2 Antibody (CAB7075)Immunohistochemistry of paraffin-embedded rat brain using TUSC2 antibody (CAB7075) at dilution of 1:200 (40x lens).
Anti-TUSC2 Antibody (CAB7075)Immunohistochemistry of paraffin-embedded mouse kidney using TUSC2 antibody (CAB7075) at dilution of 1:200 (40x lens).
Anti-TUSC2 Antibody (CAB7075)Immunohistochemistry of paraffin-embedded mouse heart using TUSC2 antibody (CAB7075) at dilution of 1:200 (40x lens).
Anti-TUSC2 Antibody (CAB7075)Immunofluorescence analysis of U2OS cells using TUSC2 antibody (CAB7075). Blue: DAPI for nuclear staining.

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