The TUFM Polyclonal Antibody (CAB6423) is a valuable tool for researchers studying TUFM, a key protein involved in mitochondrial biogenesis and energy production. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TUFM protein, researchers can accurately detect and analyze its expression in various cell types, making it ideal for investigations in mitochondrial biology and related fields.TUFM, also known as mitochondrial Tu translation elongation factor, plays a crucial role in the translation of mitochondrial genes and the maintenance of mitochondrial function. Dysregulation of TUFM has been associated with various metabolic disorders and mitochondrial dysfunction, highlighting its importance in cellular energy metabolism.
Research into TUFM can provide insights into the mechanisms underlying mitochondrial diseases and potential therapeutic strategies for improving mitochondrial function.The TUFM Polyclonal Antibody is a valuable tool for researchers interested in unraveling the complexities of mitochondrial biology and its implications for human health. By studying TUFM expression and function, researchers can enhance our understanding of mitochondrial physiology and potentially identify novel targets for therapeutic intervention in mitochondrial-related disorders.
Product Name:
TUFM Rabbit Polyclonal Antibody
SKU:
CAB6423
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 186-455 of human TUFM (NP_003312.3).
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:10 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
P43; EFTU; COXPD4; EF-TuMT; TUFM
Positive Sample:
Jurkat,HeLa
Conjugate:
Unconjugated
Cellular Localization:
Mitochondrion.
Calculated MW:
50kDa
Observed MW:
49kDa
This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
7284
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TUFM Rabbit pAb (CAB6423) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
