The Tubulin Polyclonal Antibody (CABC015) is a valuable tool for researchers studying tubulin, a protein involved in cell division, cell structure, and intracellular transport. This antibody, generated from rabbit immunizations, exhibits high reactivity with tubulin in human samples and is suitable for use in Western blot applications. By specifically binding to tubulin, this antibody enables precise detection and analysis in a variety of cell types, making it an essential reagent for studies in cell biology, cancer research, and drug development.Tubulin plays a critical role in maintaining cell shape and structure, as well as facilitating crucial processes such as mitosis and intracellular trafficking.
Dysregulation of tubulin expression or function has been implicated in diseases like cancer, neurodegenerative disorders, and developmental abnormalities. Therefore, understanding the role of tubulin and its regulatory mechanisms is essential for advancing our knowledge of these conditions and developing targeted therapies.The Tubulin Polyclonal Antibody (CABC015) offers researchers a reliable tool for investigating the function and regulation of tubulin in various biological contexts. Its high specificity and sensitivity make it an ideal choice for studies aimed at elucidating the roles of tubulin in health and disease, paving the way for new insights and potential therapeutic interventions.
Product Name:
β-Tubulin Rabbit Polyclonal Antibody
SKU:
CABC015
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-260 of human β-Tubulin (NP_006077.2).
This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13.
Purification Method:
Affinity purification
Gene ID:
203068
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using β-Tubulin Rabbit pAb (AC015) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
