The Tube1 Monoclonal Antibody (MACO0401) is a cutting-edge research tool for studying CD44, a cell surface glycoprotein involved in cell adhesion and migration. This antibody, produced using a hybridoma technique, exhibits high specificity and sensitivity towards human CD44 and is validated for use in flow cytometry and immunohistochemistry applications. By targeting the CD44 protein, researchers can accurately detect and analyze its expression in various tissues and cell types, providing invaluable insights into its role in cancer metastasis, stem cell migration, and immune cell activation.CD44, a multifunctional adhesion molecule, is known to interact with various ligands to modulate cell signaling pathways that regulate cell migration, proliferation, and survival.
Its involvement in tumor progression, metastasis, and resistance to therapy makes it a promising therapeutic target for cancer treatment. Furthermore, CD44's contribution to immune cell activation and migration underscores its importance in inflammation, autoimmune diseases, and tissue regeneration. The Tube1 Monoclonal Antibody offers researchers a powerful tool to delve into the complexities of CD44 biology and explore its potential as a diagnostic marker or therapeutic target in various pathological conditions.
Product Name:
Anti-TUBE1 Antibody
Product Sku:
MACO0401
Size:
50ug
Host Species:
Mouse
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:5000
Species Reactivity:
Human,Mouse,Rat
Immunogen:
Synthetic Peptide of Epsilon Tubulin
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Clonality:
Monoclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Background:
Synonyms:
Tubulin epsilon chain (Epsilon-tubulin)
Western blot analysis of 1) MCF7Cell Lysate, 2) Rat Brain Tissue Lysate, 3) Mouse Brain Tissue Lysate using Epsilon Tubulin Mouse mAb diluted at 1:2000.
UniProt Protein Function:
Subcellular location: Cytoplasm › cytoskeleton › microtubule organizing center › centrosome. Note: Associated with pericentriolar material. Sequence similarities: Belongs to the tubulin family.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Jan 2009]
