The TUBB8 Polyclonal Antibody (CAB8396) is a valuable tool for researchers studying TUBB8, a key protein involved in microtubule assembly and cell division. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TUBB8 protein, this antibody allows for the detection and analysis of TUBB8 in a variety of cell types, making it an ideal choice for studies in cell biology and developmental biology.TUBB8, a member of the beta-tubulin family, is essential for proper spindle formation during mitosis and plays a crucial role in maintaining the structural integrity of cells.
Dysregulation of TUBB8 has been linked to various diseases, including cancer and developmental disorders. By investigating the function and expression of TUBB8, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.Overall, the TUBB8 Polyclonal Antibody (CAB8396) provides researchers with a reliable tool for studying TUBB8 and its role in cellular processes, offering opportunities for advancement in fields such as oncology, neurobiology, and reproductive biology.
Product Name:
TUBB8 Polyclonal Antibody
SKU:
CAB8396
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-444 of human TUBB8 (NP_817124.1).
The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2 and infertility.
Purification Method:
Affinity purification
Gene ID:
347688
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TUBB8 antibody (CAB8396) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
