The TUBB8 Polyclonal Antibody (CAB12617) is a valuable tool for researchers studying TUBB8, a member of the beta-tubulin family essential for microtubule formation. This antibody is produced in rabbits and shows high reactivity with human samples, making it suitable for use in various research applications such as Western blotting.TUBB8 plays a crucial role in cell division and is particularly important for the development and function of cilia and flagella. Mutations in the TUBB8 gene have been linked to a variety of genetic disorders affecting ciliary function, highlighting the importance of studying this protein in the context of ciliopathies and related conditions.
By utilizing the TUBB8 Polyclonal Antibody, researchers can effectively detect and analyze TUBB8 expression in different cell types, furthering our understanding of its function and potential implications in disease. This antibody is a valuable tool for investigations into ciliary biology, cell division, and genetic disorders associated with TUBB8 dysfunction.
Product Name:
TUBB8 Rabbit Polyclonal Antibody
SKU:
CAB12617
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide of human TUBB8
Tested Applications:
WBIF/ICCELISA
Recommended Dilution:
WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:
OOMD; OOMD2; OZEMA2; bA631M21.2; TUBB8
Positive Sample:
LO2,Jurkat,HepG2,A-549
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, cytoskeleton.
Calculated MW:
50kDa
Observed MW:
55kDa
The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2 and infertility.
Purification Method:
Affinity purification
Gene ID:
347688
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TUBB8 antibody (CAB12617) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
