The TUBB6 Monoclonal Antibody (PAC041530) is a vital tool for researchers studying the Tubulin Beta 6 (TUBB6) protein, which plays a key role in cell division and intracellular transportation processes. This antibody is produced using hybridoma technology and is highly specific to human samples, making it an ideal choice for Western blot and immunohistochemistry applications.TUBB6 is a member of the tubulin protein family, essential for the formation of microtubules that are crucial for cell structure and function.
Dysregulation of TUBB6 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. By using the TUBB6 Monoclonal Antibody, researchers can explore the expression and localization of TUBB6 in different cell types, advancing our understanding of its role in health and disease.
Western blot. All lanes: TUBB6 antibody at 4µg/ml. Lane 1: Hela whole cell lysate. Lane 2: MDA-MB-231 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 50 kDa. Observed band size: 50 kDa.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO41530 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO41530 at dilution of 1:100.
Background:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain (By similarity).
Synonyms:
Tubulin beta-6 chain (Tubulin β class V), TUBB6
UniProt Protein Function:
TUBB6: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 18p11.21Cellular Component: microtubule; nucleus
