The TUBB3 Polyclonal Antibody (CAB17074) is a valuable tool for researchers studying TUBB3, a key protein involved in microtubule formation and cellular structure. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for experiments such as Western blotting.TUBB3, also known as beta-tubulin III, is essential for the proper functioning of the nervous system and plays a crucial role in neuronal development and function. Mutations in the TUBB3 gene have been associated with neurological disorders, making it a promising target for research in neuroscience and neurology.
By utilizing the TUBB3 Polyclonal Antibody, researchers can accurately detect and analyze TUBB3 expression levels in various cell types and tissues, allowing for a better understanding of its function and potential implications in disease development. This antibody is a valuable tool for advancing scientific knowledge in the fields of neurobiology and neurodegenerative diseases.
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
10381
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] βIII-Tubulin Rabbit pAb (CAB17074) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
