TUBB3 Monoclonal Antibody [PAT2F5AT] (CPAB0629)
- SKU:
- CPAB0629
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT2F5AT
- Applications:
- WB
- ELISA
- FC
Description
TUBB3 Monoclonal Antibody [PAT2F5AT] (CPAB0629)
The TUBB3 Polyclonal Antibody (CPAB0629) is a powerful tool for researchers studying TUBB3, a protein crucial for microtubule structure and function in cells. This antibody, produced in rabbits, shows high specificity and sensitivity for human samples, making it an excellent choice for Western blot experiments. By targeting the TUBB3 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in neuroscience, cancer research, and developmental biology.
TUBB3, also known as beta-III tubulin, is a key player in neuronal development and function, making it a target of interest in neurodegenerative diseases and brain development studies. Its involvement in microtubule dynamics also makes it relevant in cancer research, where disruptions in microtubule function can lead to abnormal cell division. By understanding the role of TUBB3 in these processes, researchers can gain insights into disease mechanisms and potentially develop targeted therapies.
Product Name: | TUBB3 Antibody |
Product Sku: | CPAB0629 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human TUBB3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TUBB3 protein 1-45 amino acids purified from Ecoli. |
Clone: | PAT2F5AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | TUBB3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | Tubulin, beta 3 class III (TUBB3), which is the major constituent of microtubules, is primarily Expressed in neurons and is involved in neurogenesis and in axon guidance and maintenance. TUBB3 binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. |
Synonyms: | Beta-4, CDCBM, CFEOM3A, TUBB4, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |