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TUBB2B Monoclonal Antibody [PAT5B2AT] (CPAB0434)

SKU:
CPAB0434
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT5B2AT
Applications:
WB
IF
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

TUBB2B Monoclonal Antibody [PAT5B2AT] (CPAB0434)

The TUBB2B Polyclonal Antibody (CPAB0434) is a valuable tool for researchers studying TUBB2B, a member of the tubulin superfamily that plays a crucial role in microtubule dynamics and cell division. This antibody, derived from rabbits, exhibits high specificity for human samples and has been validated for Western blotting applications.TUBB2B is an essential component of microtubules, which are involved in maintaining cell structure, intracellular transport, and cell division. Dysregulation of TUBB2B has been linked to various diseases, including cancer and neurodevelopmental disorders.

By targeting TUBB2B with this antibody, researchers can investigate its function in different cell types and explore its potential implications in disease pathology.This polyclonal antibody provides a reliable means of detecting and quantifying TUBB2B protein levels, making it a valuable tool for studies in cell biology, cancer research, and neurobiology. By gaining a better understanding of TUBB2B's role in cellular processes, researchers may uncover new therapeutic targets and strategies for treating diseases associated with microtubule dysfunction.

Product Name:TUBB2B Antibody
Product Sku:CPAB0434
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TUBB2b mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TUBB2b amino acids 1-445 purified from Ecoli.
Clone:PAT5B2AT.
Reactivity:Other bodies
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:TUBB2b antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:TUBB2B is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. Numerous beta Tubulin isoforms have been characterized and are expressed in mammalian tissues. Tubulin binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2b is mostly expressed in developing neurons with a dominant expression during the critical steps of corticogenesis. In addition, TUBB2B is a new critical gene involved in neuronal migration. TUBB2B is present in the nuclei and nucleoplasm, Defects in the TUBB2B gene are a cause of asymmetric polymicrogyria.
Synonyms:Tubulin beta-2B chain, TUBB2B, MGC8685, FLJ98847, bA506K6.1, DKFZp566F223, RP11-506K6.1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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