Anti-TUBB2A Antibody (MACO0111)
- SKU:
- MACO0111
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Human
- Host Species:
- Mouse
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IP
- Antibody Type:
- Monoclonal Antibody
- Conjugation:
- Unconjugated
Description
Anti-TUBB2A Antibody (MACO0111)
The TUBB2A Monoclonal Antibody (MACO0111) is a valuable tool for researchers studying TUBB2A, a member of the tubulin protein family that plays a crucial role in cell division and intracellular transport processes. This antibody, produced using hybridoma technology, demonstrates high specificity and sensitivity towards human TUBB2A protein, making it ideal for use in various applications such as Western blot, immunofluorescence, and immunohistochemistry.TUBB2A is known for its involvement in microtubule dynamics and stability, making it essential for cellular processes like mitosis, cell migration, and neuronal development. Dysregulation of TUBB2A has been linked to neurodevelopmental disorders and cancer progression, highlighting its significance as a potential therapeutic target.
Researchers studying cell biology, neuroscience, and oncology can benefit from the accurate detection and analysis of TUBB2A using this monoclonal antibody.By utilizing the TUBB2A Monoclonal Antibody (MACO0111), researchers can gain valuable insights into the function and regulation of TUBB2A in health and disease. This antibody's specificity and reliability make it a valuable asset for advancing scientific knowledge and potentially identifying new therapeutic strategies targeting TUBB2A-related pathways.
| Product Name: | Anti-TUBB2A Antibody |
| Product Sku: | MACO0111 |
| Size: | 50ug |
| Host Species: | Mouse |
| Tested Applications: | ELISA, WB, IP |
| Recommended Dilutions: | WB:1:500-1:5000, IP:1:200-1:2000 |
| Species Reactivity: | Mouse,Rat,Human |
| Immunogen: | Synthetic Peptide |
| Form: | Liquid |
| Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Purification Method: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Clonality: | Monoclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | |
| Synonyms: | Tubulin beta-2A chain |
 | Western blot analysis of 1) Mouse Brain tissue, 2) Rat Brain tissue, diluted at 1:100000. |
 | 1) Input: Mouse Brain Tissue Lysate 2) IP product: IP dilute 1: 200 Western blot analysis: primary antibody : 1: 10000 Secondary antibody: Goat anti-Mouse IgG, Light chain specific (S003), 1: 5000 |
| UniProt Protein Function: | TUBB2A: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 6p25 Cellular Component: cytoplasm; microtubule; nucleus Molecular Function:GTP binding; GTPase activity; protein binding; structural constituent of cytoskeleton Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; microtubule-based process; protein folding Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 5 |
| NCBI Summary: | Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015] |
| UniProt Code: | Q13885 |
| NCBI GenInfo Identifier: | 74762137 |
| NCBI Gene ID: | 7280 |
| NCBI Accession: | Q13885.1 |
| UniProt Secondary Accession: | Q13885,Q6FGZ8, Q8IWR2, |
| UniProt Related Accession: | Q13885 |
| Molecular Weight: | 49,907 Da |
| NCBI Full Name: | Tubulin beta-2A chain |
| NCBI Synonym Full Names: | tubulin beta 2A class IIa |
| NCBI Official Symbol: | TUBB2AÂ Â |
| NCBI Official Synonym Symbols: | TUBB; TUBB2; CDCBM5Â Â |
| NCBI Protein Information: | tubulin beta-2A chain |
| UniProt Protein Name: | Tubulin beta-2A chain |
| UniProt Synonym Protein Names: | Tubulin beta class IIa |
| Protein Family: | Tubulin |
| UniProt Gene Name: | TUBB2AÂ Â |
| UniProt Entry Name: | TBB2A_HUMAN |
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