TUBB2A Antibody (PACO30892)
- SKU:
- PACO30892
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TUBB2A Antibody (PACO30892)
The TUBB2A Polyclonal Antibody (PACO30892) is a valuable tool for researchers studying TUBB2A, a member of the tubulin protein family that is essential for cell division and intracellular transport processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically targeting the TUBB2A protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and neurology.TUBB2A is known for its crucial role in microtubule dynamics and neuronal development, making it a key player in processes such as cell division, intracellular transport, and neurite outgrowth.
Dysregulation of TUBB2A has been implicated in conditions like neuronal migration disorders, neurodevelopmental disorders, and certain cancers. By studying the function and regulation of TUBB2A with this antibody, researchers can gain insights into its involvement in these diseases and potentially identify therapeutic targets for intervention.
| Antibody Name: | TUBB2A Antibody (PACO30892) |
| Antibody SKU: | PACO30892 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Tubulin beta-2A chain protein (1-445AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: TUBB2A antibody at 14µg/ml Lane 1: MCF-7 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: MDA-MB-231 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 50 kDa Observed band size: 50 kDa . |
| Background: | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain By similarity. |
| Synonyms: | Tubulin beta-2A chain (Tubulin β class IIa), TUBB2A, TUBB2 |
| UniProt Protein Function: | TUBB2A: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 6p25 Cellular Component: cytoplasm; microtubule; nucleus Molecular Function:GTP binding; GTPase activity; protein binding; structural constituent of cytoskeleton Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; microtubule-based process; protein folding Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 5 |
| NCBI Summary: | Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015] |
| UniProt Code: | Q13885 |
| NCBI GenInfo Identifier: | 74762137 |
| NCBI Gene ID: | 7280 |
| NCBI Accession: | Q13885.1 |
| UniProt Secondary Accession: | Q13885,Q6FGZ8, Q8IWR2, |
| UniProt Related Accession: | Q13885 |
| Molecular Weight: | 49,907 Da |
| NCBI Full Name: | Tubulin beta-2A chain |
| NCBI Synonym Full Names: | tubulin beta 2A class IIa |
| NCBI Official Symbol: | TUBB2AÂ Â |
| NCBI Official Synonym Symbols: | TUBB; TUBB2; CDCBM5Â Â |
| NCBI Protein Information: | tubulin beta-2A chain |
| UniProt Protein Name: | Tubulin beta-2A chain |
| UniProt Synonym Protein Names: | Tubulin beta class IIa |
| Protein Family: | Tubulin |
| UniProt Gene Name: | TUBB2AÂ Â |
| UniProt Entry Name: | TBB2A_HUMAN |
| Antibodies |
| TUBB2A Antibody (PACO00107) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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TUBB2A Antibody (PACO00107)
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