The TUBB1 Polyclonal Antibody (CAB17779) is a valuable tool for researchers studying the protein TUBB1, a member of the tubulin superfamily involved in cell division and structure. This antibody, derived from rabbits, shows high reactivity with human samples and is specifically validated for use in Western blot applications. By binding to the TUBB1 protein, this antibody allows for the detection and analysis of TUBB1 in various cell types, making it ideal for studies in cell biology, cancer research, and neurology.TUBB1 plays a crucial role in microtubule formation and stability, essential processes for cell division, motility, and intracellular transport.
Dysregulation of TUBB1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities. Therefore, understanding the function and regulation of TUBB1 is essential for developing targeted therapies and treatment strategies for these conditions. The TUBB1 Polyclonal Antibody provides researchers with a powerful tool to explore the role of TUBB1 in health and disease.
Product Name:
Tubulin beta-1 chain Rabbit Polyclonal Antibody
SKU:
CAB17779
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-451 of human Tubulin beta-1 chain (NP_110400.1).
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
Purification Method:
Affinity purification
Gene ID:
81027
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Tubulin beta-1 chain Rabbit pAb (CAB17779) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
