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TUBA1C Antibody (PACO46302)

SKU:
PACO46302
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IP
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • TUBA1C Antibody PACO46302
  • TUBA1C Antibody PACO46302
  • TUBA1C Antibody PACO46302
€339
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Description

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TUBA1C Antibody (PACO46302)

The TUBA1C Polyclonal Antibody (PAC046302) is a valuable tool for researchers studying TUBA1C, a member of the tubulin family involved in cell division and intracellular transport processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TUBA1C protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.

TUBA1C is a key component of the cytoskeleton and plays a crucial role in maintaining cell shape and structure. Dysregulation of TUBA1C has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance as a potential therapeutic target. By gaining a better understanding of the function of TUBA1C, researchers can uncover new insights into the mechanisms underlying these diseases and potentially develop novel treatment strategies.

Antibody Name:TUBA1C Antibody (PACO46302)
Antibody SKU:PACO46302
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IP
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000
Species Reactivity:Human, Mouse
Immunogen:Recombinant Human Tubulin alpha-1C chain protein (29-184AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry of paraffin-embedded human prostate cancer using PACO46302 at dilution of 1:100.
Product ImageImmunoprecipitating TUBA1C in K562 whole cell lysate. Lane 1: Rabbit control IgG instead of PACO46302 in K562 whole cell lysate.For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/50000). Lane 2: PACO46302 (4µg) + K562 whole cell lysate (500µg). Lane 3: K562 whole cell lysate (20µg).
Product ImageWestern Blot. Positive WB detected in: K562 whole cell lysate, PC-3 whole cell lysate, U251 whole cell lysate, Mouse brain tissue. All lanes: TUBA1C antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 50 kDa. Observed band size: 50 kDa.
Background:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain.
Synonyms:Tubulin alpha-1C chain (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain], TUBA1C, TUBA6
UniProt Protein Function:TUBA1C: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family.Protein type: Cytoskeletal; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 12q13.12Cellular Component: microtubule; nucleus; vesicleMolecular Function: protein binding; structural molecule activityBiological Process: cell division; cytoskeleton-dependent intracellular transport; microtubule-based process
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9BQE3
NCBI GenInfo Identifier:20455322
NCBI Gene ID:84790
NCBI Accession:Q9BQE3.1
UniProt Secondary Accession:Q9BQE3
UniProt Related Accession:Q9BQE3
Molecular Weight:49,895 Da
NCBI Full Name:Tubulin alpha-1C chain
NCBI Synonym Full Names:tubulin alpha 1c
NCBI Official Symbol:TUBA1C  
NCBI Official Synonym Symbols:TUBA6; bcm948  
NCBI Protein Information:tubulin alpha-1C chain
UniProt Protein Name:Tubulin alpha-1C chain
UniProt Synonym Protein Names:Alpha-tubulin 6; Tubulin alpha-6 chain
Protein Family:Tubulin
UniProt Gene Name:TUBA1C  
UniProt Entry Name:TBA1C_HUMAN
Antibodies
TUBA1C Antibody (PACO12983)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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