TUBA1B Antibody (PACO46346)
- SKU:
- PACO46346
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TUBA1B Antibody (PACO46346)
The TUBA1B Polyclonal Antibody (PAC046346) is a valuable tool for researchers studying TUBA1B, a key member of the tubulin family essential for cell division and intracellular transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TUBA1B protein, researchers can accurately detect and analyze its presence in a variety of cell types, making it ideal for studies in cell biology and cancer research.
TUBA1B, a critical component of the microtubule cytoskeleton, plays a vital role in maintaining cell structure and facilitating cell division. Dysregulation of TUBA1B expression has been linked to various cellular abnormalities and diseases, including cancer. By targeting TUBA1B, researchers can gain insights into its function and potential roles in disease pathology, paving the way for the development of novel therapeutic strategies targeting TUBA1B in cancer and other related conditions.
| Antibody Name: | TUBA1B Antibody (PACO46346) |
| Antibody SKU: | PACO46346 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Tubulin alpha-1B chain protein (29-310AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: TUBA1B antibody at 12 µg/ml. Lane 1: Mouse brain tissue. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51, 38 kDa. Observed band size: 51, 34, 75 kDa.. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO46346 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO46346 at dilution of 1:100. |
| Background: | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the β chain and one at a non-exchangeable site on the α chain. |
| Synonyms: | Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain], TUBA1B |
| UniProt Protein Function: | TUBA1B: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 12q13.12 Cellular Component: microtubule; cytoplasmic microtubule Molecular Function:GTPase activity; protein binding; GTP binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding; double-stranded RNA binding; structural molecule activity Biological Process: protein polymerization; 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; cell division; cytoskeleton-dependent intracellular transport; microtubule cytoskeleton organization and biogenesis; microtubule-based process |
| UniProt Code: | P68363 |
| NCBI GenInfo Identifier: | 55977474 |
| NCBI Gene ID: | 10376 |
| NCBI Accession: | P68363.1 |
| UniProt Secondary Accession: | P68363,P68366, |
| UniProt Related Accession: | P68363 |
| Molecular Weight: | 55kDa |
| NCBI Full Name: | Tubulin alpha-1B chain |
| NCBI Synonym Full Names: | tubulin alpha 1b |
| NCBI Official Symbol: | TUBA1BÂ Â |
| NCBI Official Synonym Symbols: | K-ALPHA-1Â Â |
| NCBI Protein Information: | tubulin alpha-1B chain |
| UniProt Protein Name: | Tubulin alpha-1B chain |
| UniProt Synonym Protein Names: | Alpha-tubulin ubiquitous; Tubulin K-alpha-1; Tubulin alpha-ubiquitous chain |
| Protein Family: | Tubulin |
| UniProt Gene Name: | TUBA1BÂ Â |
| UniProt Entry Name: | TBA1B_HUMAN |
| Antibodies |
| Anti-Tubulin alpha 1b Antibody (CABC024) |
| Anti-Tubulin alpha 1b Antibody (CABC025) |
| Anti-Tubulin alpha 1b Antibody (CABC039) |
| TUBA1B Antibody (PACO12982) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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