UniProt Protein Function: | TTYH2: Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation. Belongs to the tweety family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Channel, chloride; Transporter; Transporter, ion channel; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17q25.1Cellular Component: plasma membraneMolecular Function: chloride channel activity; protein binding |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BSA4 |
NCBI GenInfo Identifier: | 53988385 |
NCBI Gene ID: | 94015 |
NCBI Accession: | NP_116035.5 |
UniProt Secondary Accession: | Q9BSA4,Q3B7H8, Q3B7R9, Q6AWB4, Q8NBB7, Q96PK1, B3KX97 |
UniProt Related Accession: | Q9BSA4 |
Molecular Weight: | 23,562 Da |
NCBI Full Name: | protein tweety homolog 2 isoform 1 |
NCBI Synonym Full Names: | tweety family member 2 |
NCBI Official Symbol: | TTYH2Â Â |
NCBI Official Synonym Symbols: | C17orf29Â Â |
NCBI Protein Information: | protein tweety homolog 2 |
UniProt Protein Name: | Protein tweety homolog 2 |
UniProt Synonym Protein Names: | |
Protein Family: | Protein tweety |
UniProt Gene Name: | TTYH2Â Â |
UniProt Entry Name: | TTYH2_HUMAN |