The TTYH2 Polyclonal Antibody (PAC063611) is a key tool for researchers studying TTYH2, a protein that plays a crucial role in various cellular processes. This antibody, produced in-house utilizing high-quality rabbit polyclonal antibodies, demonstrates strong reactivity with human samples and has been validated for use in Western blot applications.TTYH2, also known as a member of the Tweety family of chloride channels, is involved in ion transport and cell signaling pathways. Its function in cellular homeostasis and signaling makes it a promising target for studies in cell biology and neuroscience.
The TTYH2 antibody specifically binds to the TTYH2 protein, allowing for accurate detection and analysis in a variety of cell types.Researchers investigating cell signaling, ion transport, or neuronal functions will find the TTYH2 Polyclonal Antibody an invaluable tool for their experiments. By understanding the role of TTYH2 in cellular processes, researchers can gain insights into potential therapeutic strategies for diseases related to cell signaling dysregulation.
Antibody Name:
TTYH2 Antibody (PACO63611)
Antibody SKU:
PACO63611
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Protein tweety homolog 2 protein (455-534AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: TTYH2 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 22.9 kDa. Observed band size: 28 kDa.
Background:
Probable large-conductance Ca2+-activated chloride channel. May play a role in Ca2+ signal transduction. May be involved in cell proliferation and cell aggregation.
Synonyms:
Protein tweety homolog 2, hTTY2, TTYH2, C17orf29
UniProt Protein Function:
TTYH2: Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation. Belongs to the tweety family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Channel, chloride; Transporter; Transporter, ion channel; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17q25.1Cellular Component: plasma membraneMolecular Function: chloride channel activity; protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel, and may play a role in kidney tumorigenesis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
