The TTYH1 Polyclonal Antibody (PAC040794) is a valuable tool for researchers studying TTYH1, a protein involved in various cellular functions. This antibody, raised in rabbits, is highly specific for detecting TTYH1 in human samples and has been validated for use in Western blot applications.TTYH1, also known as Tweety homolog 1, is a member of the Tweety family of proteins that are implicated in ion channel activity and cell proliferation. Research suggests that TTYH1 may play a role in cancer development and progression, making it a potential target for anti-cancer therapies.
By utilizing the TTYH1 Polyclonal Antibody, researchers can investigate the expression and function of TTYH1 in different cell types and gain valuable insights into its role in cancer biology.This antibody offers a reliable and sensitive tool for studying TTYH1, making it ideal for researchers in the fields of cancer biology, cell biology, and molecular biology. By understanding the function of TTYH1, researchers may uncover new opportunities for developing targeted therapies for cancers that rely on TTYH1 activity.
Western blot. All lanes: TTYH1 antibody at 4µg/ml + Raji whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 50, 27, 36 kDa. Observed band size: 50 kDa.
Immunofluorescent analysis of Hela cells using PACO40794 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Probable chloride channel. May be involved in cell adhesion (By similarity).
Synonyms:
Protein tweety homolog 1 (hTTY1), TTYH1
UniProt Protein Function:
TTYH1: Probable chloride channel. May be involved in cell adhesion. Belongs to the tweety family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, ion channelChromosomal Location of Human Ortholog: 19q13.4Cellular Component: integral to membrane; plasma membraneMolecular Function: chloride channel activityBiological Process: chloride transport
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jan 2011]
