The TTLL12 Polyclonal Antibody (CAB19994) is a valuable tool for researchers studying TTLL12, a member of the tubulin tyrosine ligase-like protein family implicated in various cellular processes. This rabbit-derived antibody is highly specific and reacts strongly with TTLL12 in human samples, making it ideal for Western blot applications. By binding to the TTLL12 protein, this antibody enables the detection and analysis of this important molecule in different cell types.TTLL12 is known to play a role in microtubule dynamics and cilium formation, suggesting its involvement in key cellular functions such as cell division and signaling.
Research on TTLL12 has implications in developmental biology, ciliopathies, and cancer biology, making this antibody a valuable tool for investigating the functions and mechanisms of TTLL12 in various biological contexts.By using the TTLL12 Polyclonal Antibody, researchers can gain valuable insights into the role of TTLL12 in cellular processes and disease pathways, ultimately advancing our understanding of this intriguing protein and its potential as a therapeutic target in human health and disease.
Product Name:
[KO Validated] TTLL12 Rabbit Polyclonal Antibody
SKU:
CAB19994
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 485-644 of human TTLL12 (NP_055955.1).
cytoplasm, microtubule organizing center, nucleus, spindle
Calculated MW:
74kDa
Observed MW:
80kDa
Enables H4K20me3 modified histone binding activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
23170
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and TTLL12 knockout (KO) 293T cells, using [KO Validated] TTLL12 Rabbit pAb (CAB19994) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
