The TTF2 Polyclonal Antibody (CAB7751) is a valuable tool for research involving TTF2, a transcription termination factor that plays a critical role in regulating gene expression. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.TTF2 is involved in the termination of transcription by RNA polymerase II and has been implicated in various cellular processes, including RNA processing and DNA repair. By targeting TTF2, researchers can investigate its function in different cell types and gain insights into its role in transcriptional regulation.
This antibody is ideal for studies in molecular biology, genetics, and cancer research, where understanding the mechanisms of gene expression control is essential. By using the TTF2 Polyclonal Antibody, researchers can detect and analyze TTF2 protein levels, leading to a better understanding of its function and potential implications in disease states.
Product Name:
TTF2 Rabbit Polyclonal Antibody
SKU:
CAB7751
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TTF2 (NP_003585.3).
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing.
Purification Method:
Affinity purification
Gene ID:
8458
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TTF2 antibody (CAB7751) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
