The TTF1 Rabbit Polyclonal Antibody (CAB18128) is a valuable tool for researchers studying thyroid transcription factor 1 (TTF1), a protein involved in the regulation of gene expression in the thyroid and lung tissues. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to TTF1, this antibody enables the detection and analysis of TTF1 protein levels in various cell types, making it ideal for studies focusing on thyroid and lung biology, as well as cancer research.TTF1 is a transcription factor that plays a crucial role in the differentiation and development of thyroid and lung tissues.
It is also involved in regulating the expression of genes associated with cell growth, proliferation, and differentiation. Understanding the function of TTF1 is essential for uncovering its role in various physiological and pathological processes, such as thyroid cancer and respiratory diseases. By using the TTF1 Rabbit Polyclonal Antibody, researchers can further explore the molecular mechanisms underlying TTF1-mediated gene regulation and its implications in disease development.
Product Name:
TTF1 Rabbit Polyclonal Antibody
SKU:
CAB18128
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 806-905 of human TTF1 (NP_031370.2).
This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression.
Purification Method:
Affinity purification
Gene ID:
7270
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of U-2 OS cells using TTF1 Rabbit pAb (CAB18128) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
