The TTC30A Polyclonal Antibody (PACO37566) is a powerful tool for researchers studying TTC30A, a protein involved in ciliogenesis and cilia function. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards TTC30A in human samples, making it an ideal choice for Western blot applications. By binding to the TTC30A protein, this antibody enables precise detection and analysis in a variety of cell types, facilitating research in the fields of cell biology and developmental biology.TTC30A, also known as tetratricopeptide repeat domain 30A, plays a crucial role in the formation and function of cilia, important organelles involved in cell motility and signal transduction.
Dysfunction of TTC30A has been linked to ciliopathies, a group of genetic disorders characterized by abnormal cilia structure and function. By studying the function of TTC30A, researchers can gain insights into the mechanisms underlying ciliogenesis and cilia-related diseases.The TTC30A Polyclonal Antibody is a valuable tool for investigating the roles of TTC30A in cellular processes and diseases associated with cilia dysfunction. Its specificity and reliability make it an essential component of any research project aiming to elucidate the functions of TTC30A and its implications in health and disease.
Western blot. All lanes: TTC30A antibody at 0.1µg/ml + Mouse gonadal tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 77 kDa. Observed band size: 77 kDa.
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO37566 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO37566 at dilution of 1:100.
Background:
Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
Synonyms:
Tetratricopeptide repeat protein 30A (TPR repeat protein 30A), TTC30A
UniProt Protein Function:
Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
