The TTC26 Antibody (PAC058961) is a polyclonal antibody designed for research involving TTC26, a protein involved in ciliogenesis and ciliary function. The antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for studies in cell biology and genetics.TTC26 is an essential protein for the assembly and function of primary cilia, which play a crucial role in various cellular processes, including signaling pathways and cell cycle regulation. Dysregulation of cilia formation and function has been linked to a range of developmental disorders and diseases, making TTC26 a key target for research in these areas.
This antibody is validated for use in Western blot applications, enabling the detection and analysis of TTC26 in different cell types and tissues. Its high specificity and reactivity make it a valuable tool for researchers studying ciliopathies, developmental disorders, and other conditions related to ciliary dysfunction. By understanding the role of TTC26 in cellular processes, researchers can gain insights into disease mechanisms and potentially identify therapeutic targets for ciliopathies and related disorders.
Antibody Name:
TTC26 Antibody (PACO58961)
Antibody SKU:
PACO58961
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Intraflagellar transport protein 56 protein (5-122AA)
Western Blot. Positive WB detected in: NIH/3T3 whole cell lysate, K562 whole cell lysate, Hela whole cell lysate. All lanes: TTC26 antibody at 2.45µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 65, 57, 61 kDa. Observed band size: 57 kDa.
Background:
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI3 at the ciliary tip and its dissociation from SUFU.
Synonyms:
Intraflagellar transport protein 56 (Tetratricopeptide repeat protein 26) (TPR repeat protein 26), TTC26, IFT56
