The TTC11/FIS1 Polyclonal Antibody is a valuable tool for researchers studying TTC11 and FIS1, two proteins involved in mitochondrial dynamics and quality control. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to TTC11 and FIS1 proteins, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in cell biology, metabolism, and mitochondrial function.
TTC11 and FIS1 are integral players in maintaining mitochondrial health and function, crucial for cellular energy production and overall cell health. Dysregulation of these proteins has been implicated in various diseases, including neurodegenerative disorders and metabolic syndromes. Studying the role and regulation of TTC11 and FIS1 with this antibody may provide valuable insights into the mechanisms underlying these conditions and potential therapeutic targets for intervention.
Product Name:
TTC11/FIS1 Polyclonal Antibody
SKU:
CAB21527
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human TTC11/FIS1 (NP_057152.2).
Enables identical protein binding activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; cellular calcium ion homeostasis; and mitochondrion organization. Acts upstream of or within mitochondrion morphogenesis. Located in mitochondrion and peroxisome. Is integral component of mitochondrial outer membrane and integral component of peroxisomal membrane. Part of protein-containing complex. Biomarker of Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
51024
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various lysates, using TTC11/FIS1 antibody (CAB21527) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
