TTC1 Antibody (PACO27541)
- SKU:
- PACO27541
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TTC1 Antibody (PACO27541)
The TTC1 Polyclonal Antibody (PACO27541) is an essential tool for researchers studying TTC1, a protein involved in various cellular processes, including cell proliferation and differentiation. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to the TTC1 protein, researchers can accurately detect and analyze its expression in a variety of cell types.TTC1, also known as tetratricopeptide repeat domain 1, is a key player in cellular homeostasis and may play a role in diseases such as cancer and neurodegenerative disorders.
By investigating the function and regulation of TTC1, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially develop targeted therapies. The TTC1 Polyclonal Antibody is a valuable tool for advancing research in the fields of cell biology and disease pathology.
| Antibody Name: | TTC1 Antibody (PACO27541) |
| Antibody SKU: | PACO27541 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Tetratricopeptide repeat protein 1 protein (3-292AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: TTC1 antibody at 2µg/ml Lane 1: 293T whole cell lysate Lane 2: EC109 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 34 kDa Observed band size: 45 kDa . |
| Background: | Interacts with the GAP domain of NF1. |
| Synonyms: | Tetratricopeptide repeat protein 1 (TPR repeat protein 1), TTC1, TPR1 |
| UniProt Protein Function: | TTC1: Interacts with the GAP domain of NF1. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 5q33.3 Cellular Component: peroxisomal membrane; cytoplasm Molecular Function:protein binding; unfolded protein binding Biological Process: protein folding |
| NCBI Summary: | This gene encodes a protein that belongs to the tetratrico peptide repeat superfamily of proteins. The encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q99614 |
| NCBI GenInfo Identifier: | 543173164 |
| NCBI Gene ID: | 7265 |
| NCBI Accession: | NP_001269429.1 |
| UniProt Secondary Accession: | Q99614,Q9BVT3, B2RCT2, D3DQJ8, |
| UniProt Related Accession: | Q99614 |
| Molecular Weight: | 33,526 Da |
| NCBI Full Name: | tetratricopeptide repeat protein 1 |
| NCBI Synonym Full Names: | tetratricopeptide repeat domain 1 |
| NCBI Official Symbol: | TTC1Â Â |
| NCBI Official Synonym Symbols: | TPR1Â Â |
| NCBI Protein Information: | tetratricopeptide repeat protein 1; TPR repeat protein 1 |
| UniProt Protein Name: | Tetratricopeptide repeat protein 1 |
| UniProt Gene Name: | TTC1Â Â |
| UniProt Entry Name: | TTC1_HUMAN |
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