The TTBK2 Polyclonal Antibody (CAB7609) is a valuable tool for researchers studying TTBK2, a key protein involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific to human TTBK2 and is validated for use in Western blot applications. By targeting the TTBK2 protein, this antibody allows for the detection and analysis of TTBK2 expression in a wide range of cell types, making it an essential tool for research in the fields of cell biology and neuroscience.TTBK2, also known as tau-tubulin kinase 2, is critical for the regulation of microtubule dynamics and plays a crucial role in maintaining cellular structure and function.
Dysregulation of TTBK2 has been implicated in various diseases, including neurodegenerative disorders such as Alzheimer's disease. By studying the activity of TTBK2, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention. Overall, the TTBK2 Polyclonal Antibody (CAB7609) is a reliable and effective tool for investigating the function of TTBK2 in cellular processes and disease pathways, providing valuable information for the development of novel treatments and therapies.
Product Name:
TTBK2 Rabbit Polyclonal Antibody
SKU:
CAB7609
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1185-1244 of human TTBK2 (NP_775771.3).
This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.
Purification Method:
Affinity purification
Gene ID:
146057
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from rat brain, using TTBK2 Rabbit pAb (CAB7609) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
