The TSSC1 Monoclonal Antibody (PAC017330) is a valuable tool for researchers studying TSSC1, a protein involved in telomere maintenance and cell aging processes. This antibody, developed using cutting-edge technology, specifically targets TSSC1 in human samples, making it a reliable tool for various research applications such as immunofluorescence and flow cytometry.TSSC1, also known as Telomeric Shelterin Complex Component 1, is essential for protecting telomeres and maintaining genomic stability. Dysregulation of TSSC1 has been linked to accelerated aging and increased risk of cancer development.
By targeting TSSC1 with this monoclonal antibody, researchers can better understand the role of TSSC1 in cellular processes and potentially develop targeted therapies for age-related diseases and cancer.Don't miss out on the opportunity to enhance your research with the TSSC1 Monoclonal Antibody (PAC017330). Ensure the reliability and accuracy of your results by using this high-quality antibody validated for use in various experimental settings. Start exploring the role of TSSC1 in telomere biology and aging processes today.
Antibody Name:
TSSC1 Antibody (PACO17330)
Antibody SKU:
PACO17330
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human TSSC1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17330(TSSC1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11.
Synonyms:
tumor suppressing subtransferable candidate 1
UniProt Protein Function:
TSSC1: Chromosomal Location of Human Ortholog: 2p25.3
UniProt Protein Details:
NCBI Summary:
This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008]
