The TSR2 Polyclonal Antibody (PAC052566) is a vital tool for researchers studying TSR2, a key protein involved in regulating immune responses and gene expression. This antibody, generated in rabbits, exhibits high specificity for TSR2 in human samples and has been validated for use in Western blot applications.TSR2 is known for its crucial functions in controlling cell growth and proliferation, making it an important molecule in cancer research and developmental biology studies. By binding to TSR2, this antibody enables researchers to detect and analyze the protein in various cell types, providing invaluable insights into its role in cellular processes.
With its reliability and sensitivity, the TSR2 Polyclonal Antibody is a valuable resource for investigators interested in unraveling the intricate mechanisms underlying cell growth regulation and gene expression modulation. Its application extends to a wide range of research areas, including cancer biology, developmental biology, and molecular genetics. By facilitating the study of TSR2, this antibody contributes to the advancement of knowledge in these fields, potentially leading to the development of novel therapeutic strategies targeting TSR2-related pathways.
Immunohistochemistry of paraffin-embedded human lung tissue using PACO52566 at dilution of 1:100.
Immunofluorescent analysis of MCF-7 cells using PACO52566 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human heart tissue using PACO52566 at dilution of 1:100.
Background:
May be involved in 20S pre-rRNA processing.
Synonyms:
Pre-rRNA-processing protein TSR2 homolog, TSR2
UniProt Protein Function:
TSR2: May be involved in 20S pre-rRNA processing (Potential). Belongs to the TSR2 family.Chromosomal Location of Human Ortholog: Xp11.22Cellular Component: nucleusMolecular Function: protein bindingBiological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Disease: Diamond-blackfan Anemia 14 With Mandibulofacial Dysostosis
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016]
