The TSR1 Polyclonal Antibody (CAB4842) is specially designed for research involving TSR1, a protein involved in ribosome biogenesis and cellular growth regulation. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in Western blot applications. It specifically binds to the TSR1 protein, enabling accurate detection and analysis in various cell types, making it an ideal tool for studies in molecular biology and cancer research.TSR1, also known as ribosome biogenesis protein TSR1 homolog, is essential for ribosome assembly and plays a crucial role in protein synthesis. Dysregulation of TSR1 has been linked to cancer development and progression, making it a promising target for therapeutic interventions.
By studying the function and expression of TSR1, researchers can gain valuable insights into the mechanisms underlying cancer and potentially identify novel therapeutic strategies targeting this protein. The TSR1 Polyclonal Antibody is a valuable tool for researchers interested in understanding the role of TSR1 in cellular processes, particularly in the context of cancer biology. Its high specificity and sensitivity make it a reliable choice for experiments aiming to unravel the molecular pathways involving TSR1 and its implications for disease development.
Product Name:
TSR1 Rabbit Polyclonal Antibody
SKU:
CAB4842
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 455-804 of human TSR1 (NP_060598.3).
Enables RNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of preribosome, small subunit precursor.
Purification Method:
Affinity purification
Gene ID:
55720
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TSR1 Rabbit pAb (CAB4842) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
