The TSPEAR Polyclonal Antibody (PAC015728) is specifically designed for research involving TSPEAR, a protein that plays a crucial role in various cellular processes. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in applications such as Western blotting. It binds specifically to the TSPEAR protein, allowing for accurate detection and analysis in a range of cell types, making it an excellent tool for research in molecular biology and biochemistry.TSPEAR, also known as tumor suppressor candidate 2, is involved in the regulation of cell growth, differentiation, and apoptosis, making it a potential target for studying cancer and other diseases.
Understanding the function of TSPEAR can provide valuable insights into the mechanisms underlying these conditions, and may lead to the development of novel therapeutic approaches. The TSPEAR Polyclonal Antibody is a valuable tool for researchers looking to explore the role of TSPEAR in various biological processes.
Antibody Name:
TSPEAR Antibody (PACO15728)
Antibody SKU:
PACO15728
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Fusion protein of human TSPEAR
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15728(TSPEAR Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15728(TSPEAR Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a protein that contains a N-terminal thrombospondin-type laminin G domain and several tandem arranged epilepsy-associated repeats (EARs). A mutation in this gene is the cause of autosomal recessive deafness-98. Alternate splicing results in multiple transcript variants.
Synonyms:
thrombospondin-type laminin G domain and EAR repeats
UniProt Protein Function:
TSPEAR: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 21q22.3Cellular Component: cell surface; stereociliumBiological Process: sensory perception of soundDisease: Deafness, Autosomal Recessive 98
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that contains a N-terminal thrombospondin-type laminin G domain and several tandem arranged epilepsy-associated repeats (EARs). A mutation in this gene is the cause of autosomal recessive deafness-98. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
