The TSPAN8 Polyclonal Antibody (CAB13266) is a vital tool for researchers studying TSPAN8, a tetraspanin protein involved in cell adhesion, migration, and signaling pathways. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot and immunohistochemistry applications.TSPAN8 is known to play a role in cancer progression and metastasis, making it a promising target for cancer research and therapy development. By detecting and analyzing TSPAN8 expression in various cell types, this antibody allows researchers to gain insights into the function of TSPAN8 in cancer biology and potentially identify new therapeutic targets.
The TSPAN8 Polyclonal Antibody is a valuable asset for studies in oncology, cell biology, and metastasis research. Its ability to specifically bind to TSPAN8 protein enables researchers to investigate its role in tumor growth, invasion, and other cellular processes, ultimately advancing our understanding of cancer biology and potentially leading to the development of novel treatment strategies.
Product Name:
TSPAN8 Rabbit Polyclonal Antibody
SKU:
CAB13266
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-200 of human TSPAN8 (NP_004607.1).
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7103
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TSPAN8 Rabbit pAb (CAB13266) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.