The Tetraspanin-7 Polyclonal Antibody (CAB6417) is a valuable tool for researchers studying Tetraspanin-7, a member of the tetraspanin family involved in cell adhesion, migration, and signaling. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By targeting the Tetraspanin-7 protein, this antibody enables researchers to detect and analyze Tetraspanin-7 expression in a variety of cell types, making it useful for studies in cell biology and cancer research.Tetraspanin-7 plays a crucial role in mediating cell-cell interactions and signal transduction processes, making it a potential target for therapeutic intervention in diseases such as cancer and inflammatory disorders.
Understanding the function and regulation of Tetraspanin-7 can provide valuable insights into the mechanisms underlying these diseases and pave the way for the development of novel treatment strategies. Researchers interested in exploring the role of Tetraspanin-7 in cellular processes and disease pathogenesis will find this antibody to be a valuable asset in their research endeavors.
Product Name:
TSPAN7 Rabbit Polyclonal Antibody
SKU:
CAB6417
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human TSPAN7 (NP_004606.2).
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.
Purification Method:
Affinity purification
Gene ID:
7102
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse spleen, using TSPAN7 antibody (CAB6417) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
