The TSPAN6 Polyclonal Antibody (CAB17540) is a valuable tool for researchers studying TSPAN6, a member of the tetraspanin family known to be involved in various cellular processes such as cell adhesion, migration, and signaling. This antibody, produced in rabbits, shows high specificity and reactivity towards human samples, making it suitable for Western blot applications. By targeting the TSPAN6 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it an essential reagent for studies in cell biology and cancer research.TSPAN6 is a key player in mediating cell-to-cell interactions and signal transduction processes, making it a potential target for therapeutic interventions in diseases such as cancer and neurological disorders.
Research on TSPAN6 has revealed its involvement in modulating cell proliferation, invasion, and metastasis, highlighting its potential as a prognostic marker and therapeutic target in various pathological conditions. By utilizing the TSPAN6 Polyclonal Antibody, researchers can further explore the functional significance of TSPAN6 and its potential implications in disease progression and treatment strategies.
Product Name:
TSPAN6 Rabbit Polyclonal Antibody
SKU:
CAB17540
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-200 of human TSPAN6 (NP_003261.1).
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing.
Purification Method:
Affinity purification
Gene ID:
7105
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using TSPAN6 Rabbit pAb (CAB17540) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
