TSPAN6 Rabbit Polyclonal Antibody (CAB17540)
- SKU:
- CAB17540
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | TSPAN6 Rabbit Polyclonal Antibody |
SKU: | CAB17540 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-200 of human TSPAN6 (NP_003261.1). |
Sequence: | NSFK NNYE KALK QYNS TGDY RSHA VDKI QNTL HCCG VTDY RDWT DTNY YSEK GFPK SCCK LEDC TPQR DADK VNNE GCFI K |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | T245; TM4SF6; TSPAN-6; TSPAN6 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | extracellular exosome, plasma membrane |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing.
Purification Method: | Affinity purification |
Gene ID: | 7105 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |