The Tspan18 Monoclonal Antibody (PACO60304) is a valuable tool for researchers studying the Tspan18 protein, which is involved in cell adhesion and signaling pathways. This antibody, generated in mice, is highly specific to human samples and has been validated for use in various applications, including immunofluorescence and flow cytometry.Tspan18, a member of the tetraspanin superfamily, plays a crucial role in cell-cell interactions and intracellular signaling processes. Its expression has been implicated in various physiological and pathological processes, including cancer progression and immune response modulation.
The Tspan18 Monoclonal Antibody enables researchers to detect and analyze Tspan18 expression in different cell types, providing valuable insights into its function and potential as a therapeutic target.By understanding the role of Tspan18 in cellular processes, researchers can uncover novel mechanisms underlying disease development and progression. The Tspan18 Monoclonal Antibody is a powerful tool for investigating the function of Tspan18 in various contexts, making it an essential component of studies in cancer biology, immunology, and cell biology.
Antibody Name:
TSPAN18 Antibody (PACO60304)
Antibody SKU:
PACO60304
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Tetraspanin-18 protein (151-223AA)
Immunofluorescence staining of Hela cells with PACO60304 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
integral component of plasma membrane, cell surface receptor signaling pathway
Synonyms:
Tetraspanin-18 (Tspan-18), TSPAN18
UniProt Protein Function:
TSPAN18: Belongs to the tetraspanin (TM4SF) family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11p11.2Cellular Component: integral to plasma membraneBiological Process: cell surface receptor linked signal transduction
