The TSN Polyclonal Antibody (CAB18590) is a highly specific research tool for studying TSN, a cell surface protein involved in immune regulation. This antibody, produced in rabbits, boasts high reactivity with human samples and has been validated for Western blot applications. By binding to the TSN protein, this antibody enables accurate detection and analysis across various cell types, making it a valuable asset for researchers in immunology and cancer studies.TSN, also known as translin, plays a pivotal role in regulating immune responses and inflammation, making it a promising target for research in cancer, autoimmune diseases, and chronic inflammatory disorders.
By delving into the functions of TSN, researchers can uncover new insights into immune system modulation, leading to the development of innovative therapies for a range of conditions. Gain a deeper understanding of immune regulation with the TSN Polyclonal Antibody.
Product Name:
TSN Rabbit Polyclonal Antibody
SKU:
CAB18590
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1).
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7247
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TSN Rabbit pAb (CAB18590) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
