TSN Rabbit Polyclonal Antibody (CAB18590)
- SKU:
- CAB18590
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | TSN Rabbit Polyclonal Antibody |
SKU: | CAB18590 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human TSN (NP_004613.1). |
Sequence: | GFQD IPKR CLKA REHF GTVK THLT SLKT KFPA EQYY RFHE HWRF VLQR LVFL AAFV VYLE TETL VTRE AVTE ILGI EPDR EKGF HLDV EDYL SGVL ILAS E |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | C3PO; RCHF1; TBRBP; TRSLN; BCLF-1; REHF-1; TSN |
Positive Sample: | K-562,HeLa,Mouse spleen,Mouse brain,Rat thymus,Rat spleen |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 26kDa |
Observed MW: | 26kDa |
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7247 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |